1. Workflow Is a Biosafety Control In high-containment laboratories, safety is not only maintained by walls, filters, or PPE—it also depends on how people, samples, and materials move through the space. Effective biosafety labs are designed around unidirectional workflow, where clean and contaminated zones are clearly separated, and every process supports containment. 2. What Is Unidirectional [...]
Intorduction to Laboratory Infrastructure Solutions LIS Profile August 2025
LIS Profile August 2025 LIS Profile August 2025
Interior of BSL-3 laboratory 1. From Routine Testing to Risk Management Many diagnostic and research facilities operate with minimal containment infrastructure, even when handling potentially hazardous specimens. As biological risks escalate—from local TB outbreaks to global pandemics—higher biosafety standards are no longer optional. Biosafety laboratories are not simply regulatory checkboxes. They are critical infrastructure for [...]
Executive Summary High containment laboratories, including Biosafety Level 3 (BSL-3) and Biosafety Level 4 (BSL-4) facilities, handle some of the world’s most dangerous pathogens. These environments rely on tightly controlled engineering systems—including ventilation, filtration, access control, power, and waste management—to maintain safe operations. Remote monitoring technologies have become essential for sustaining biosafety, operational resilience, and [...]
Executive Summary Ventilation systems are the primary engineering control in high containment laboratories. They manage airborne hazards, prevent environmental contamination, and protect personnel. This white paper explains how ventilation supports design, and operation, with emphasis on airflow control, pressure cascading, filtration, and regulatory compliance. 1. Introduction Ventilation is both a functional necessity and a statutory [...]
Executive Summary Filtration is the primary defense in laboratory ventilation systems, particularly in biosafety level 2 (BSL-2) and biosafety level 3 (BSL-3) environments where airborne biological hazards may be present. Prefilters and secondary filters are essential for capturing particulate matter, preventing environmental contamination, and preserving the efficiency and integrity of high-efficiency particulate air (HEPA) filters. [...]
Establishing a biosafety level 3 (BSL-3) laboratory is a major investment in institutional capability, scientific infrastructure, and public health security. These laboratories are designed for the safe diagnosis and study of airborne infectious agents such as Mycobacterium tuberculosis, SARS-CoV-2, and other high-consequence pathogens. Whether the objective is to expand diagnostic capacity, strengthen outbreak response, or [...]
